How Lung Repair Works

Our lungs are essential for life. They allow oxygen to enter our body and remove waste gases when we breathe out

Healthy lungs are constantly maintained and repaired. Tiny air sacs in the lungs can be damaged by infections, pollution, or normal wear and tear. When this happens, the body activates a repair system.

MC002 is MimeCure’s lead therapy and is based on a protein that naturally occurs in the human body. This protein plays an important role in how lung tissue stays healthy and repairs itself after damage.

When Lung Repair Fails

In COPD and IPF, this repair process becomes disrupted.

In COPD, lung damage continues over many years. The repair cells struggle to replace lost air sacs, and the lungs gradually lose their ability to take in oxygen. The communication between repair cells and supporting cells becomes weaker, leading to incomplete or ineffective healing.

In IPF, the repair system becomes overactive in the wrong way. Instead of healthy repair, fibroblasts produce too much scar tissue. This scarring makes the lungs stiff and makes breathing more difficult. At the same time, the cells that normally help rebuild healthy lung tissue can no longer do their job properly.

In both diseases, the result is the same: the lungs cannot repair themselves as they should.

Special repair cells (often called stem cells) help replace damaged lung cells. At the same time, supporting cells in the lung tissue (fibroblasts) help by providing structure and signals that guide healing. When these cells communicate well with each other, damaged lung tissue can heal in a balanced and controlled way, keeping the lungs flexible and functional.

Helping The Lungs Heal

  • Calming supporting cells in the lung, so they are less likely to form stiff scar tissue

  • Supporting the lung’s repair (stem) cells, helping them replace damaged lung tissue

  • Restoring communication between repair cells and supporting cells, allowing the healing process to regain balance

Rather than only treating symptoms, MC002 is designed to support the lung’s own repair system and address the root causes of damage.

Inhalable Lung Therapy

To work as effectively as possible, MC002 is delivered directly to the lungs by inhalation. MimeCure has developed a dry powder form that can be inhaled, allowing the therapy to reach the parts of the lung where damage occurs and repair is needed.

By delivering the treatment straight to the lungs, MC002 can act exactly where the disease is located. This targeted approach means that smaller amounts of the therapy may be sufficient and helps limit effects on the rest of the body.

By combining regenerative science with inhalation technology, MimeCure aims to develop a treatment that is effective and easy for patients to use.